glomax-multi+ detection system plate reader (Promega)
90
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Promega
glomax-multi+ detection system plate reader
Glomax Multi+ Detection System Plate Reader, supplied by Promega, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glomax-multi++detection+system+plate+reader/glomax+20+20+luminometer/pmc10742381__pnas__2311396120__sapp-64-11-16
Average 90 stars, based on 1 article reviews
Glomax Multi+ Detection System Plate Reader, supplied by Promega, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/glomax-multi++detection+system+plate+reader/glomax+20+20+luminometer/pmc10742381__pnas__2311396120__sapp-64-11-16
Average 90 stars, based on 1 article reviews
glomax-multi+ detection system plate reader - by Bioz Stars,
2026-09
90/100 stars
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Luciferase:Article Title: Elevated microRNA-187 causes cardiac endothelial dysplasia to promote congenital heart disease through inhibition of NIPBL Article Snippet: Luciferase activity was measured using a Article Title: Synthesis of a Phosphoethanolamine Cellulose Mimetic and Evaluation of Its Unanticipated Biofilm Modulating Properties. Article Snippet: Following overnight incubation, bacterial density was quantified through absorbance readings at an optical density at 600 nm (OD600) using a Article Title: In vitro trypanocidal potency and in vivo treatment efficacy of oligomeric ethylene glycol-tethered nitrofurantoin derivatives. Article Snippet: Janse van Rensburg et al. European Journal of Pharmaceutical Sciences 192 (2024) 106668 European Journal of Article Title: Discovery and Development of First-in-Class ACKR3/CXCR7 Superagonists for Platelet Degranulation Modulation. Article Snippet: The atypical chemokine receptor 3 (ACKR3), formerly known as CXC-chemokine receptor 7 (CXCR7), has been postulated to regulate platelet function and thrombus formation.. Herein, we report the discovery and development of first-in-class ACKR3 agonists, which demonstrated superagonistic properties with Emax values of up to 160% compared to the endogenous reference ligand CXCL12 in a β-arrestin recruitment assay.. Initial in silico screening using an ACKR3 homology model identified two hits, C10 (EC50 19.1 μM) and C11 (EC50 = 11.4 μM). Article Title: In vitro trypanocidal potency and in vivo treatment efficacy of oligomeric ethylene glycol-tethered nitrofurantoin derivatives. Article Snippet: Briefly, Nunc MicroWell 96-well optical bottom plates (Thermo Fisher Scientific) containing 50 μL of the bloodstream form of either T. b. gambiense strain IL1922, T. b. rhodesiense strain IL1501, T. b. brucei strain GUTat3.1 (2.5 × 103 cells/mL), T. congolense strain IL3000 (1 × 105 cells/mL), T. evansi strain Tansui, or T. equiperdum strain IVM-t1 (1 × 104 cells/mL) and 50 μL of the test compound solution two times serially diluted at seven different concentrations (highest: 3.125 ug/ml; lowest: 1.525 ng/mL) were incubated at 37 ◦C and 5 % CO2 (33 ◦C for T. congolense strain IL3000) for 72 h. Then, the condition of the bloodstream-form trypanosomes was observed with phase-contrast microscopy, and subsequently, 25 μL of the Article Title: The expression of different gene constructs in Escherichia coli SM lux biosensor after exposure to drugs Article Snippet: The analyses were performed using the Article Title: Novel Small-Molecule Atypical Chemokine Receptor 3 Agonists: Design, Synthesis, and Pharmacological Evaluation for Antiplatelet Therapy. Article Snippet: ACKR3, an atypical chemokine receptor, has been associated with prothrombotic events and the development of cardiovascular events.. We designed, synthesized, and evaluated a series of novel small molecule ACKR3 agonists.. Extensive structure−activity relationship studies resulted in several promising agonists with potencies ranging from the low micromolar to nanomolar range, for example, 23 (EC50 = 111 nM, Emax = 95%) and 27 (EC50 = 69 nM, Emax = 82%) in the β-arrestin-recruitment assay. Article Title: Synthesis of a Phosphoethanolamine Cellulose Mimetic and Evaluation of Its Unanticipated Biofilm Modulating Properties Article Snippet: Following overnight incubation, Activity Assay:Article Title: Elevated microRNA-187 causes cardiac endothelial dysplasia to promote congenital heart disease through inhibition of NIPBL Article Snippet: Luciferase activity was measured using a Article Title: Synthesis of a Phosphoethanolamine Cellulose Mimetic and Evaluation of Its Unanticipated Biofilm Modulating Properties. Article Snippet: Following overnight incubation, bacterial density was quantified through absorbance readings at an optical density at 600 nm (OD600) using a Article Title: In vitro trypanocidal potency and in vivo treatment efficacy of oligomeric ethylene glycol-tethered nitrofurantoin derivatives. Article Snippet: Janse van Rensburg et al. European Journal of Pharmaceutical Sciences 192 (2024) 106668 European Journal of Article Title: Discovery and Development of First-in-Class ACKR3/CXCR7 Superagonists for Platelet Degranulation Modulation. Article Snippet: The atypical chemokine receptor 3 (ACKR3), formerly known as CXC-chemokine receptor 7 (CXCR7), has been postulated to regulate platelet function and thrombus formation.. Herein, we report the discovery and development of first-in-class ACKR3 agonists, which demonstrated superagonistic properties with Emax values of up to 160% compared to the endogenous reference ligand CXCL12 in a β-arrestin recruitment assay.. Initial in silico screening using an ACKR3 homology model identified two hits, C10 (EC50 19.1 μM) and C11 (EC50 = 11.4 μM). Article Title: In vitro trypanocidal potency and in vivo treatment efficacy of oligomeric ethylene glycol-tethered nitrofurantoin derivatives. Article Snippet: Briefly, Nunc MicroWell 96-well optical bottom plates (Thermo Fisher Scientific) containing 50 μL of the bloodstream form of either T. b. gambiense strain IL1922, T. b. rhodesiense strain IL1501, T. b. brucei strain GUTat3.1 (2.5 × 103 cells/mL), T. congolense strain IL3000 (1 × 105 cells/mL), T. evansi strain Tansui, or T. equiperdum strain IVM-t1 (1 × 104 cells/mL) and 50 μL of the test compound solution two times serially diluted at seven different concentrations (highest: 3.125 ug/ml; lowest: 1.525 ng/mL) were incubated at 37 ◦C and 5 % CO2 (33 ◦C for T. congolense strain IL3000) for 72 h. Then, the condition of the bloodstream-form trypanosomes was observed with phase-contrast microscopy, and subsequently, 25 μL of the Article Title: The expression of different gene constructs in Escherichia coli SM lux biosensor after exposure to drugs Article Snippet: The analyses were performed using the Article Title: Novel Small-Molecule Atypical Chemokine Receptor 3 Agonists: Design, Synthesis, and Pharmacological Evaluation for Antiplatelet Therapy. Article Snippet: ACKR3, an atypical chemokine receptor, has been associated with prothrombotic events and the development of cardiovascular events.. We designed, synthesized, and evaluated a series of novel small molecule ACKR3 agonists.. Extensive structure−activity relationship studies resulted in several promising agonists with potencies ranging from the low micromolar to nanomolar range, for example, 23 (EC50 = 111 nM, Emax = 95%) and 27 (EC50 = 69 nM, Emax = 82%) in the β-arrestin-recruitment assay. Article Title: Synthesis of a Phosphoethanolamine Cellulose Mimetic and Evaluation of Its Unanticipated Biofilm Modulating Properties Article Snippet: Following overnight incubation, Incubation:Article Title: Elevated microRNA-187 causes cardiac endothelial dysplasia to promote congenital heart disease through inhibition of NIPBL Article Snippet: Luciferase activity was measured using a Article Title: Synthesis of a Phosphoethanolamine Cellulose Mimetic and Evaluation of Its Unanticipated Biofilm Modulating Properties. Article Snippet: Following overnight incubation, bacterial density was quantified through absorbance readings at an optical density at 600 nm (OD600) using a Article Title: In vitro trypanocidal potency and in vivo treatment efficacy of oligomeric ethylene glycol-tethered nitrofurantoin derivatives. Article Snippet: Janse van Rensburg et al. European Journal of Pharmaceutical Sciences 192 (2024) 106668 European Journal of Article Title: Discovery and Development of First-in-Class ACKR3/CXCR7 Superagonists for Platelet Degranulation Modulation. Article Snippet: The atypical chemokine receptor 3 (ACKR3), formerly known as CXC-chemokine receptor 7 (CXCR7), has been postulated to regulate platelet function and thrombus formation.. Herein, we report the discovery and development of first-in-class ACKR3 agonists, which demonstrated superagonistic properties with Emax values of up to 160% compared to the endogenous reference ligand CXCL12 in a β-arrestin recruitment assay.. Initial in silico screening using an ACKR3 homology model identified two hits, C10 (EC50 19.1 μM) and C11 (EC50 = 11.4 μM). Article Title: In vitro trypanocidal potency and in vivo treatment efficacy of oligomeric ethylene glycol-tethered nitrofurantoin derivatives. Article Snippet: Briefly, Nunc MicroWell 96-well optical bottom plates (Thermo Fisher Scientific) containing 50 μL of the bloodstream form of either T. b. gambiense strain IL1922, T. b. rhodesiense strain IL1501, T. b. brucei strain GUTat3.1 (2.5 × 103 cells/mL), T. congolense strain IL3000 (1 × 105 cells/mL), T. evansi strain Tansui, or T. equiperdum strain IVM-t1 (1 × 104 cells/mL) and 50 μL of the test compound solution two times serially diluted at seven different concentrations (highest: 3.125 ug/ml; lowest: 1.525 ng/mL) were incubated at 37 ◦C and 5 % CO2 (33 ◦C for T. congolense strain IL3000) for 72 h. Then, the condition of the bloodstream-form trypanosomes was observed with phase-contrast microscopy, and subsequently, 25 μL of the Article Title: The expression of different gene constructs in Escherichia coli SM lux biosensor after exposure to drugs Article Snippet: The analyses were performed using the Article Title: Novel Small-Molecule Atypical Chemokine Receptor 3 Agonists: Design, Synthesis, and Pharmacological Evaluation for Antiplatelet Therapy. Article Snippet: ACKR3, an atypical chemokine receptor, has been associated with prothrombotic events and the development of cardiovascular events.. We designed, synthesized, and evaluated a series of novel small molecule ACKR3 agonists.. Extensive structure−activity relationship studies resulted in several promising agonists with potencies ranging from the low micromolar to nanomolar range, for example, 23 (EC50 = 111 nM, Emax = 95%) and 27 (EC50 = 69 nM, Emax = 82%) in the β-arrestin-recruitment assay. Article Title: Synthesis of a Phosphoethanolamine Cellulose Mimetic and Evaluation of Its Unanticipated Biofilm Modulating Properties Article Snippet: Following overnight incubation, Microscopy:Article Title: Elevated microRNA-187 causes cardiac endothelial dysplasia to promote congenital heart disease through inhibition of NIPBL Article Snippet: Luciferase activity was measured using a Article Title: Synthesis of a Phosphoethanolamine Cellulose Mimetic and Evaluation of Its Unanticipated Biofilm Modulating Properties. Article Snippet: Following overnight incubation, bacterial density was quantified through absorbance readings at an optical density at 600 nm (OD600) using a Article Title: In vitro trypanocidal potency and in vivo treatment efficacy of oligomeric ethylene glycol-tethered nitrofurantoin derivatives. Article Snippet: Janse van Rensburg et al. European Journal of Pharmaceutical Sciences 192 (2024) 106668 European Journal of Article Title: Discovery and Development of First-in-Class ACKR3/CXCR7 Superagonists for Platelet Degranulation Modulation. Article Snippet: The atypical chemokine receptor 3 (ACKR3), formerly known as CXC-chemokine receptor 7 (CXCR7), has been postulated to regulate platelet function and thrombus formation.. Herein, we report the discovery and development of first-in-class ACKR3 agonists, which demonstrated superagonistic properties with Emax values of up to 160% compared to the endogenous reference ligand CXCL12 in a β-arrestin recruitment assay.. Initial in silico screening using an ACKR3 homology model identified two hits, C10 (EC50 19.1 μM) and C11 (EC50 = 11.4 μM). Article Title: In vitro trypanocidal potency and in vivo treatment efficacy of oligomeric ethylene glycol-tethered nitrofurantoin derivatives. Article Snippet: Briefly, Nunc MicroWell 96-well optical bottom plates (Thermo Fisher Scientific) containing 50 μL of the bloodstream form of either T. b. gambiense strain IL1922, T. b. rhodesiense strain IL1501, T. b. brucei strain GUTat3.1 (2.5 × 103 cells/mL), T. congolense strain IL3000 (1 × 105 cells/mL), T. evansi strain Tansui, or T. equiperdum strain IVM-t1 (1 × 104 cells/mL) and 50 μL of the test compound solution two times serially diluted at seven different concentrations (highest: 3.125 ug/ml; lowest: 1.525 ng/mL) were incubated at 37 ◦C and 5 % CO2 (33 ◦C for T. congolense strain IL3000) for 72 h. Then, the condition of the bloodstream-form trypanosomes was observed with phase-contrast microscopy, and subsequently, 25 μL of the Article Title: The expression of different gene constructs in Escherichia coli SM lux biosensor after exposure to drugs Article Snippet: The analyses were performed using the Article Title: Novel Small-Molecule Atypical Chemokine Receptor 3 Agonists: Design, Synthesis, and Pharmacological Evaluation for Antiplatelet Therapy. Article Snippet: ACKR3, an atypical chemokine receptor, has been associated with prothrombotic events and the development of cardiovascular events.. We designed, synthesized, and evaluated a series of novel small molecule ACKR3 agonists.. Extensive structure−activity relationship studies resulted in several promising agonists with potencies ranging from the low micromolar to nanomolar range, for example, 23 (EC50 = 111 nM, Emax = 95%) and 27 (EC50 = 69 nM, Emax = 82%) in the β-arrestin-recruitment assay. Article Title: Synthesis of a Phosphoethanolamine Cellulose Mimetic and Evaluation of Its Unanticipated Biofilm Modulating Properties Article Snippet: Following overnight incubation, Lysis:Article Title: Elevated microRNA-187 causes cardiac endothelial dysplasia to promote congenital heart disease through inhibition of NIPBL Article Snippet: Luciferase activity was measured using a Article Title: Synthesis of a Phosphoethanolamine Cellulose Mimetic and Evaluation of Its Unanticipated Biofilm Modulating Properties. Article Snippet: Following overnight incubation, bacterial density was quantified through absorbance readings at an optical density at 600 nm (OD600) using a Article Title: In vitro trypanocidal potency and in vivo treatment efficacy of oligomeric ethylene glycol-tethered nitrofurantoin derivatives. Article Snippet: Janse van Rensburg et al. European Journal of Pharmaceutical Sciences 192 (2024) 106668 European Journal of Article Title: Discovery and Development of First-in-Class ACKR3/CXCR7 Superagonists for Platelet Degranulation Modulation. Article Snippet: The atypical chemokine receptor 3 (ACKR3), formerly known as CXC-chemokine receptor 7 (CXCR7), has been postulated to regulate platelet function and thrombus formation.. Herein, we report the discovery and development of first-in-class ACKR3 agonists, which demonstrated superagonistic properties with Emax values of up to 160% compared to the endogenous reference ligand CXCL12 in a β-arrestin recruitment assay.. Initial in silico screening using an ACKR3 homology model identified two hits, C10 (EC50 19.1 μM) and C11 (EC50 = 11.4 μM). Article Title: In vitro trypanocidal potency and in vivo treatment efficacy of oligomeric ethylene glycol-tethered nitrofurantoin derivatives. Article Snippet: Briefly, Nunc MicroWell 96-well optical bottom plates (Thermo Fisher Scientific) containing 50 μL of the bloodstream form of either T. b. gambiense strain IL1922, T. b. rhodesiense strain IL1501, T. b. brucei strain GUTat3.1 (2.5 × 103 cells/mL), T. congolense strain IL3000 (1 × 105 cells/mL), T. evansi strain Tansui, or T. equiperdum strain IVM-t1 (1 × 104 cells/mL) and 50 μL of the test compound solution two times serially diluted at seven different concentrations (highest: 3.125 ug/ml; lowest: 1.525 ng/mL) were incubated at 37 ◦C and 5 % CO2 (33 ◦C for T. congolense strain IL3000) for 72 h. Then, the condition of the bloodstream-form trypanosomes was observed with phase-contrast microscopy, and subsequently, 25 μL of the Article Title: The expression of different gene constructs in Escherichia coli SM lux biosensor after exposure to drugs Article Snippet: The analyses were performed using the Article Title: Novel Small-Molecule Atypical Chemokine Receptor 3 Agonists: Design, Synthesis, and Pharmacological Evaluation for Antiplatelet Therapy. Article Snippet: ACKR3, an atypical chemokine receptor, has been associated with prothrombotic events and the development of cardiovascular events.. We designed, synthesized, and evaluated a series of novel small molecule ACKR3 agonists.. Extensive structure−activity relationship studies resulted in several promising agonists with potencies ranging from the low micromolar to nanomolar range, for example, 23 (EC50 = 111 nM, Emax = 95%) and 27 (EC50 = 69 nM, Emax = 82%) in the β-arrestin-recruitment assay. Article Title: Synthesis of a Phosphoethanolamine Cellulose Mimetic and Evaluation of Its Unanticipated Biofilm Modulating Properties Article Snippet: Following overnight incubation, |